For over 50 years, Substance Use & Misuse (formerly The International Journal of the Addictions) has provided a unique international multidisciplinary venue for the exchange of original research, theories, policy analyses, and unresolved issues concerning substance use and misuse (licit and illicit drugs, alcohol, nicotine, and eating disorders). Guest editors for special issues devoted to single topics of current concern are invited.Topics covered include:Clinical trials and clinical research (treatment and prevention of substance misuse and related infectious diseases)Epidemiology of substance misuse and related infectious diseasesSocial pharmacologyMeta-analyses and systematic reviewsTranslation of scientific findings to real world clinical and other settingsAdolescent and student-focused researchState of the art quantitative and qualitative researchPolicy analysesNegative results and intervention failures that are instructiveValidity studies of instruments, scales, and tests that are generalizableCritiques and essays on unresolved issuesAuthors can choose to publish gold open access in this journal.