Bioscience Reports provides a home for sound scientific research in all areas of cell biology and molecular life sciences.Since 2012, Bioscience Reports has been fully Open Access and publishes all papers under the liberal CC BY licence, giving the life science community quality research to share and discuss.Content before 2012 is subscription-only, and is accessible via archive purchase. Articles are assessed on soundness, providing a home for valid findings and data.We welcome papers that span disciplines (e.g. chemistry, medicine), including papers describing:-new methodologies-tools and reagents to probe biological questions-mechanistic details-disease mechanisms-metabolic processes and their regulation-structure and function-bioenergetics