The articles in TrAC are concise, critical overviews of new developments in analytical chemistry, which are aimed at helping analytical chemists and other users of analytical techniques. These critical reviews comprise excellent, up-to-date, timely coverage of topics of interest in analytical chemistry, such as: analytical instrumentation, biomedical analysis, biomolecular analysis, biosensors, chemical analysis, chemometrics, clinical chemistry, drug discovery, environmental analysis and monitoring, food analysis, forensic science, laboratory automation, materials science, metabolomics, pesticide-residue analysis, pharmaceutical analysis, proteomics, surface science, and water analysis and monitoring.General issues contain critical review articles. Special Issues provide comprehensive updates with critical review articles on particularly topical fields of interest in analytical chemistry.