Nature Reviews Canceraims to be the premier source of reviews and commentaries for the scientific communities we serve. We strive to publish articles that are authoritative, accessible and enhanced with clearly understandable figures, tables and other display items. We want to provide an unparalleled service to authors, referees and readers,and we work hard to maximize the usefulness and impact of each article. The journal publishesResearch Highlights, Comments, Reviews and Perspectives relevant to cancer researchers, with ourbroad scopeensuring that the articles we publishreachthe widest possible audience.